Spotlight on Antidiabetic Agents with Cardiovascular or Renoprotective Benefits
نویسندگان
چکیده
منابع مشابه
Combining insulins with oral antidiabetic agents: effect on hyperglycemic control, markers of cardiovascular risk and disease
Patients with type 2 diabetes mellitus (T2DM) have an increased risk of cardiovascular disease (CVD). Unfortunately, several potential barriers exist for CVD risk management in diabetes, including the need for significant lifestyle changes, potential problems with hypoglycemia, weight gain, injection tolerability, treatment complexity with current diabetes therapies and other, unmodifiable fact...
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The prevalence of type 2 diabetes mellitus (T2DM) has increased rapidly over the past decade. In the Untied States, this increase has been greater than 40%. Obesity, which is closely linked to risk of developing T2DM, has likewise increased in prevalence by more than 60% during the same time period. Cardiovascular disease is the major cause of mortality among patients with T2DM, accounting for ...
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OBJECTIVE To review the literature on the association between antidiabetic agents and morbidity and mortality in people with heart failure and diabetes. DESIGN Systematic review and meta-analysis of controlled studies (randomised trials or cohort studies) evaluating antidiabetic agents and outcomes (death and admission to hospital) in patients with heart failure and diabetes. DATA SOURCES E...
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The aim of the present study was to investigate the antidiabetic and renal protective effect of Momordica dioica extract (MDMtE) in streptozotocin-diabetic rats. MDMtE treatment markedly reduced serum glucose, increased serum insulin and urea levels. Study results indicated that the antioxidant enzyme activity of kidney was increased, while thiobarbituric acid reactive substances (TBARS) were r...
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The traditional oral pharmacological therapy for type 2 diabetes mellitus (T2DM) has been based on the prescription of metformin, a biguanide, as first line antihyperglycemic agent world over. It has been demonstrated that after 3 years of treatment, approximately 50% of diabetic patients could achieve acceptable glucose levels with monotherapy; but by 9 years this had declined to only 25%. The...
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ژورنال
عنوان ژورنال: The Permanente Journal
سال: 2018
ISSN: 1552-5775
DOI: 10.7812/tpp/18-034